Ülo Langel's lab
The group was formed in 2007 by Prof ÜLO LANGEL, and is dedicated to developing drug delivery strategies. The group focuses in special peptides that can be used for this purpose – the CELL-PENETRATING PEPTIDES (CPP).
The main focus is on intracellular delivery of nucleic acid based biomolecules (siRNA, plasmid DNA, SCO etc). This is useful for wide range of applications in biotechnology. However, the ultimate goal is achieving efficient delivery of macromolecules in vivo and applying this in gene therapy in man.
The group is executing its peptide and polymer chemistry experience for the development and synthesis of drug carrier systems. These systems are assessed in cell culture systems. Finally, the drug delivery efficacy is validated using in vivo models.
langelslab [ät] gmail.com